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Este mes en... Contraception
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Este mes en... Contraception:
Perinatal outcomes including long-term neuropsychiatric hospitalizations of offspring conceived during intrauterine contraceptive device use To investigate short-term adverse perinatal outcomes and long-term neuropsychiatric hospitalizations through 18years of age in offspring conceived during copper intrauterine device (IUD) use.
Abortion Providers' experiences and views on self-managed medication abortion, an exploratory study Data on the practice of self-managed medication abortion are limited, in part because this practice takes place purposefully outside of established healthcare systems. Given this, we aimed to ascertain abortion providers' familiarity with self-managed medication abortion and associated complications, compare regional differences, and evaluate provider attitudes.
Electronic interventions for changing knowledge, attitudes, or practices regarding contraception: a systematic review We conducted a systematic review of the effectiveness of electronic health education tools designed to improve knowledge, attitudes or practices related to contraception.
An exploratory study of the perception of contraceptive safety and impact on lactation among postpartum nurses at women and infants hospital in 2017 To describe contraceptive knowledge and counseling practices of postpartum nurses.
Contraceptive use and childbirth rates by service branch during the first 24 months on active duty in the United States military from 2013 to 2018: a retrospective cohort analysis To measure the association of military branch-specific contraceptive education and access policy during basic training with contraceptive use and childbirth among new recruits.
Can a social media campaign increase the use of long-acting reversible contraception? Evidence from a cluster randomized control trial using Facebook To test whether an informational campaign carried out on social media increased use of long-acting reversible contraception (LARC).
Implementing best practices for the provision of long-acting reversible contraception: a survey of obstetrician-gynecologists To examine obstetrician-gynecologists' practices regarding provision of long-acting reversible contraceptive (LARC) methods same-day, immediately postpartum, or to women under age 21.STUDY DESIGN: Between August 2016 and March 2017, the American College of Obstetricians and Gynecologists (ACOG) sent 2500 of their members an electronic survey questionnaire regarding the provision of LARC methods. ACOG mailed nonresponders paper surveys.
Unintentional IUD expulsion with concomitant menstrual cup use: a case series Although reproductive age women use both menstrual cups and intrauterine devices (IUDs) simultaneously, it is unknown whether concomitant use reduces contraceptive effectiveness. We report seven cases wherein IUD expulsion occurred during concomitant menstrual cup use. Further research is needed to determine mechanisms of expulsion, predictors, and strategies to avoid expulsions.
Real world data on Nexplanon® procedure-related events: final results from the Nexplanon observational risk assessment study (NORA) We conducted this study to characterize the frequency of insertion-, localization- and removal-related events and their clinically significant consequences among Nexplanon® (etonogestrel radiopaque contraceptive implant) users in the United States during standard clinical practice.
“Provoked” feto-maternal hemorrhage may represent insensible cell exchange in pregnancies from 6–22weeks gestational age To quantify spontaneous and provoked fetal to maternal cell exchange in the first half of pregnancy. Transfer of fetal red blood cells (FRBCs) into the maternal circulation during the first half of pregnancy is poorly characterized but of clinical relevance for miscarriage management and invasive procedures.
Intimate partner violence, pregnancy intention and contraceptive use in Honduras Objective(s).We explored the relationship between Intimate Partner Violence (IPV), pregnancy intention and contraceptive use in Honduras.
Antifertility effectiveness of a novel polymer matrix composite and its influence on the endometrium in rhesus macaques (Macaca mulatta) Objective(s).To explored the antifertility effectiveness and influence on the endometrium of a micro-copper/low-density polyethylene/methyl vinyl silicone rubber (Cu/LDPE/MVQ) composite in rhesus macaques.
“It's not something you talk about really”: information barriers encountered by women who travel long distances for abortion care For individuals traveling significant distances for time-sensitive abortion care, accurate information about service options and locations is critical, but little is known regarding information barriers that individuals may encounter and strategies for circumventing these barriers.
Medical conditions, pregnancy perspectives, and contraceptive decision-making among young people: an exploratory, qualitative analysis To explore perspectives on family planning among young people who perceive they are infertile or will have difficulty carrying a pregnancy to term owing to medical conditions or procedures.
Relationship between patient characteristics and serum etonogestrel concentrations in contraceptive implant users To determine whether serum etonogestrel concentrations in contraceptive implant users are associated with certain individual patient characteristics.
Response re: A non-inferiority randomized controlled trial to compare transabdominal and transvaginal sonography for eligibility assessment prior to medical abortion To whom it may concern,
Video counseling about emergency contraception, an observational study This study assesses emergency contraception (EC) dispensed before and after a 3-min video counseling intervention on EC.
Impact of the contraceptive implant on maternal and neonatal morbidity and mortality in rural Papua New Guinea: a retrospective observational cohort study Using routinely collected birth data, this study sought to measure changes in maternal and neonatal morbidity and mortality after introduction of the levonorgestrel contraceptive implant into a large, rural island population in Papua New Guinea (PNG).
Opportunistic salpingectomy during postpartum contraception procedures at elective and unscheduled cesarean delivery To compare intra- and postoperative surgical complications of opportunistic bilateral total salpingectomy during postpartum permanent contraception procedures in elective and unscheduled cesarean delivery.
The Lactational Effects of Contraceptive Hormones: an Evaluation (LECHE) Study To estimate the proportion of women for whom use of hormonal contraception was associated with reporting a decreased breast milk supply.
Letter to the editor re: “A noninferiority randomized controlled trial to compare transabdominal and transvaginal sonography for eligibility assessment prior to medical abortion” We read with great interest the manuscript entitled “A noninferiority randomized controlled trial to compare transabdominal and transvaginal sonography for eligibility assessment prior to medical abortion” by Dr. Fu and colleagues .
“Repeal and replace”: increased demand for intrauterine devices following the 2016 presidential election To evaluate public's interest in contraceptive options following heightened focus on a repeal of the Affordable Care Act (ACA) since the 2016 United States presidential election.
WITHDRAWN: Fighting for access: Research at that National Abortion Federation’s 43rd Annual Meeting
Effect of theory-based contraception comics on subjective contraceptive knowledge: a pilot study We assessed the effect on subjective knowledge of a pilot educational comic decision aid about contraceptive methods.
Pilot study on functional performance and acceptability of two new synthetic adhesive male condoms (Wondaleaf): a randomized cross-over trial This study compared the condom failure rate, safety and acceptability of two new synthetic adhesive male condoms, Wondaleaf-Cap® (WLC) and Wondaleaf-On-Man® (WLM), with a marketed latex external condom Durex®-Together (DT).
Bone turnover markers in women participating in a dose-finding trial of a contraceptive vaginal ring releasing Nestorone and estradiol To evaluate changes in the bone turnover markers CTx and P1NP during 6 months' use of novel continuous contraceptive vaginal rings delivering Nestorone (NES) 200 mcg/day and three doses of estradiol (E2) (10, 20, and 40 mcg/day).
Safety of levonorgestrel 52 mg intrauterine system compared to copper intrauterine device: a population-based cohort study To compare the risk of all-cause death, hospitalizations (any cause), ectopic pregnancy, pelvic inflammatory disease or infection, uterine perforation, device removal, neuro-psychiatric drugs initiation, or new psychiatric visit(s) between levonorgestrel (LNG) 52 mg intrauterine system (IUS) and copper intrauterine device (IUD) users in France.
Access to contraception in local health departments, four Midwest states, 2017–2018 Describe contraception availability at local health departments (LHDs) serving largely rural populations.
Foregoing Rh testing and anti-D immunoglobulin for women presenting for early abortion: a recommendation from the National Abortion Federation's Clinical Policies Committee Early abortion continues to expand outside of traditional clinics, through telemedicine, self-managed medication abortion, or in smaller offices that do not specialize in obstetrical care. Consequently, requiring Rh testing and anti-D immunoglobulin as part of abortion care is becoming a barrier. As of early 2019, the Society of Family Planning , the American College of Obstetricians and Gynecologists , and the Society of Obstetricians and Gynecologists of Canada  recommend that all Rh D-negative women receive anti-D immunoglobulin after an induced abortion, regardless of gestational age or type of procedure.
Neurovascular anatomy of the adult female medial arm in relationship to potential sites for insertion of the etonogestrel contraceptive implant Anatomic assessment of the medial upper arm to identify potential sites for insertion of the etonogestrel (ENG) implant.
Challenging unintended pregnancy as an indicator of reproductive autonomy For many years, most of us in the Society of Family Planning and the wider reproductive health community have relied on the number of unintended pregnancies as a justification for our research and as a rationale for the subsidy, expansion or improvement of family planning services. We regularly draw on estimates of the proportion of all pregnancies that are unintended to show that there is a problem in need of a solution, and the papers that have provided these estimates are among the most cited in our field [1–4].
Acceptability of the Woman's Condom in a phase III multicenter open-label study This study aimed to evaluate the acceptability of the Woman's Condom (WC) over 6 months (183 days) and ≥6 menstrual cycles in a US-based multicenter open-label phase III contraceptive efficacy trial.
Bleeding and spotting with the levonorgestrel 13.5 mg intrauterine system: the impact of insertion timing To assess the impact of early versus late menstrual cycle insertion on bleeding/spotting in the 90 days following levonorgestrel (LNG) 13.5 mg intrauterine system (IUS) insertion.
Intrauterine mepivacaine instillation for pain relief during intrauterine device insertion in nulliparous women: a double-blind, randomized, controlled trial To evaluate whether intrauterine mepivacaine instillation before intrauterine device (IUD) insertion decreases pain compared to placebo.
Early abortion with buccal versus sublingual misoprostol alone: a multicenter, randomized trial To compare efficacy, safety/side effects and acceptability of buccal versus sublingual administration of a misoprostol-only regimen commonly used for early medical abortion.
Segesterone acetate/ethinyl estradiol 12-month contraceptive vaginal system safety evaluation To evaluate safety outcomes from clinical studies of a 12-month contraceptive vaginal system (CVS) releasing an average of segesterone acetate (SA) 150 mcg and ethinyl estradiol (EE) 13 mcg daily.
Study of contraceptive mobile app fails to provide convincing findings This is the third study by the company Natural Cycles on their product, a mobile phone fertility tracking app, based on an algorithm that relies primarily on basal body temperature shifts and menstrual cycle lengths . The first two studies by Bergund Scherwitzl et al. have already been criticized .
F5-peptide enhances the efficacy of the non-hormonal male contraceptive adjudin The bioavailability of the non-hormonal male contraceptive adjudin is low in rats due to the blood-testis barrier (BTB). This study was designed to examine if F5-peptide, an endogenously produced reversible BTB modifier, could enhance the bioavailability of adjudin to affect spermatogenesis and provide a contraceptive effect in rats while reducing systemic toxicity.
Looking back while moving forward: a justice-based, intersectional approach to research on contraception and disability For the first time in the 21st century, we have an emerging body of research regarding contraceptive use among adult women with disabilities in the United States.We highlight key findings from population-based analyses that found higher odds of female sterilization and lower odds of long-acting reversible contraception use among women with disabilities compared to their peers without disabilities. We consider potential reasons underlying these differences, including discriminatory attitudes and policies that restrict the sexual and reproductive autonomy of people with disabilities.
Factors associated with provision of depot medroxyprogesterone acetate to adolescents by US health care providers Identify factors associated with healthcare providers' frequency of depot medroxyprogesterone acetate (DMPA) provision to adolescents.
Claims for contraceptive services among young women filling chronic opioid prescriptions To describe claims for contraceptive services among reproductive-aged women filling chronic opioid prescriptions.
Patient recommendations for PrEP information dissemination at family planning clinics in Atlanta, Georgia Family planning (FP) clinics are an ideal setting to disseminate information about pre-exposure prophylaxis (PrEP), but little is known about women's preferences for learning about PrEP in this setting.
Pharmacokinetics of the 1.5 mg levonorgestrel emergency contraceptive in women with normal, obese and extremely obese body mass index To assess the pharmacokinetics (PK) of levonorgestrel after 1.5 mg oral doses (LNG-EC) in women with normal, obese and extremely obese body mass index (BMI).
Pregnancy outcomes after removal of osmotic dilators in patients who presented for second-trimester abortion The objective was to report pregnancy outcomes and potentially related complications among 13 patients who had osmotic dilators placed for second-trimester dilation and evacuation (D&E) followed by subsequent removal with the intention to continue their pregnancies.
Shared negative experiences of long-acting reversible contraception and their influence on contraceptive decision-making: a multi-methods study We explored how negative stories about long-acting reversible contraception (LARC) — defined as a firsthand negative experience with LARC shared directly with the study participant — were involved in participants’ decisions about whether to use LARC following abortion, and how counseling affected the influence of negative LARC stories on contraceptive choices.
A sensitive and robust UPLC–MS/MS method for quantitation of estrogens and progestogens in human serum With the widespread use of sex-steroid hormones in contraceptives and hormone replacement therapy, there is an increasing need for reliable analytical methods. We report the development of a sensitive and robust UPLC–MS/MS method for quantitation of both endogenous and synthetic sex-steroid hormones in human serum.
Uptake of permanent contraception among women in sub-Saharan Africa: a literature review of barriers and facilitators Uptake of permanent contraception among women remains low in sub-Saharan Africa compared to other regions. We aimed to synthesize available evidence on barriers to, and facilitators of permanent contraception with regards to tubal ligation among women in sub-Saharan Africa.
Effect of staff training and cost support on provision of long-acting reversible contraception in community health centers To compare the proportion of women receiving same-day long-acting reversible contraception (LARC) between two different models of contraceptive provision adapted from the Contraceptive CHOICE Project.
Rebound of medication abortion in Texas following updated mifepristone label In 2013, Texas House Bill 2 (HB 2) placed restrictions on the use of medication abortion, which later were nullified with the 2016 FDA-approved mifepristone label.
Altered pharmacokinetics of combined oral contraceptives in obesity — multistudy assessment The objective was to evaluate the pharmacokinetics (PKs) of levonorgestrel (LNG)-containing combined oral contraceptives (COCs) in obese women.
Contraceptive use at first intercourse is associated with subsequent sexual behaviors Women's contraceptive use at first sexual intercourse (FSI) may be associated with subsequent sexual behaviors. We examined associations between contraceptive methods used at FSI and subsequent number of lifetime partners, induced abortions and sexually transmitted infections (STIs).
Could second-trimester medical abortion be offered as a day service? Assessing the feasibility of a 1-day outpatient procedure using pooled data from six clinical studies Current service delivery models for second-trimester medical abortion typically include routine inpatient admission and overnight stays. To assess the feasibility of a day-service model, we evaluated outpatient administration of abortion medications and analyzed the proportion of clients who could avoid an overnight stay. We also examined additional key elements of medical abortion care to evaluate the practicality of this model.
One-year continuation of postpartum intrauterine contraceptive device: findings from a retrospective cohort study in India To evaluate outcomes of a national postpartum (within 48 h of delivery) copper intrauterine device placement (PPCuIUD) program in six “high-focus states” with high unmet family planning need in India.
Pharmacokinetic, biologic and epidemiologic differences in MPA- and NET-based progestin-only injectable contraceptives relative to the potential impact on HIV acquisition in women Access to safe and effective contraceptive choices is a reproductive right and contributes tremendously to improvements in maternal and child health. Progestin-only injectables, particularly intramuscularly injected depot medroxyprogesterone acetate (DMPA-IM), have received increased attention given findings suggesting a potential association with increased HIV risk. For women at high risk of HIV, the World Health Organization's Medical eligibility criteria for contraceptive use currently aggregate recommendations for all progestin-only injectables, including DMPA-IM, subcutaneously injected DMPA (DMPA-SC) and intramuscularly injected norethindrone/ norethisterone enanthate (NET-EN), except in the case of some drug interactions.
Characterizing pharmacist-prescribed hormonal contraception services and users in California and Oregon pharmacies This study describes hormonal contraception services provided by pharmacists and characterizes patient populations utilizing the service at one supermarket-based pharmacy chain in California and Oregon.
A pilot study of levonorgestrel concentrations and bleeding patterns in women with epilepsy using a levonorgestrel IUD and treated with antiepileptic drugs We explored levonorgestrel (LNG) concentrations, bleeding patterns and endometrial thickness in women with epilepsy (WWE) initiating an LNG-intrauterine device (IUD) co-administered with antiepileptic drugs (AEDs).
Prospective quantification of fetomaternal hemorrhage with dilation and evacuation procedures To describe fetomaternal hemorrhage (FMH) during second-trimester dilation and evacuation (D&E) to evaluate if Rhesus-immune globulin (RhIG) 100 mcg (used in the United Kingdom) and 300 mcg (used in the United States) provide adequate prophylaxis.